CD226: Master Regulator in Immunity //
CD226+ CD4 T cells' Hidden Talents?
T cell function is regulated by signals through T cell activating and inhibitory receptors. We have recently, shown that CD226 is important for the fitness of tumour-infiltrating CD8+ T cells and the efficacy of cancer immunotherapies (Braun et al., 2020).
In this project, we aim to understand the relevance of CD226 for CD4+ T cell differentiation and function in infectious diseases and cancer.
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